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The nonenzymatic initial reaction between 1 M roGFP2 WT (S 2 ) and physiological millimolar GSH concentrations was too slow to be detectable and to be of any relevance in the presence of glutaredoxins in accordance with previous analyses 32
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It helps to protect cells from free radical damage, neutralizes toxins, and aids in the production of other antioxidants like vitamins C and E
It is also an excretory route for cholesterol, bilirubin and many compounds that are too large, lipid- soluble or transporter-dependent for direct renal elimination
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