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miRNA-205 can also activate liver cancer stem cell subsets and maintain the characteristics of liver cancer stem cells by regulating the upstream target PLC-1, which is closely related to the recurrence and metastasis of liver cancer (16)

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Finally, to address potential pleiotropic effects, we excluded SNPs associated with other potential confounders identified through PhenoScanner ( Outcome sources To minimize potential bias due to population diversity, we restricted our drug target MR analysis to participants of European ancestry

There has also been a lot of attention paid to the effects that GLP-1 drugs may have on the mind, particularly whether they increase suicidal thoughts