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Schagen Journal: Cosmetics Journal ranking: Q2 Key takeaways: Topical peptides like copper tripeptide, palmitoyl pentapeptide-4, and carnosine show promising anti-aging results in controlled in vivo studies
Science 376 , eabl4896 (2022)
Who should not take GLP-1s GLP-1s in all forms are unsuitable for people who: are pregnant or breastfeeding do not meet the eligibility criteria have a family history of medullary thyroid carcinoma (MTC) or multiple endocrine neoplasia syndrome type 2 (MEN2) Medical Perspective Patients with needle phobia, a preference for pill-based routines, or good adherence to oral administration guidelines may be better suited to oral GLP-1 formulations like semaglutide (Rybelsus, Wegovy), which can enhance treatment acceptance and potentially offer strong glycemic or weight control
The evidence base supporting its use draws from studies on CJC-1295, Ipamorelin, and established GHRH/GHRP co-stimulation models, collectively informing research into pulsatile endocrine signaling, metabolic pathway regulation, and tissue-level responses under controlled experimental conditions
