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"Weight loss itself, especially if rapid, can cause itching," Goldenberg says
Polyethylene glycol (PEG) is one of the rare synthetic polymers approved by the FDA for in vivo injection, which has low relative molecular weight polydispersity, good aqueous phase and organic solubility, and is widely used in the modification of protein drugs
They also suppress appetite as well as regulate energy homeostasis by stimulating the secretion of hormones such as GLP-1 from intestinal L cells (De Silva and Bloom, 2012)
By extending earlier preclinical work on GLP-1 receptor agonists and alcohol intake to a task that directly assesses the subjective effects of alcohol, these findings provide important context for interpreting clinical observations of reduced drinking behavior among individuals receiving GLP-1 receptor agonist-based therapies
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