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Circ Res 82:314320
The comparison is therefore partly apples-to-oranges: retatrutide is a finished multi-mechanism molecule, whereas cagrilintides headline performance depends on the partner it is combined with
They work through different mechanisms that complement each other, which is why most recovery-peptide clinics prescribe them as a stack rather than asking patients to choose
Whether this differentiation satisfies the FDA's requirements is an open question
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