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Yes, metformin is still first-line for many patients, especially those without significant cardiovascular or renal risk
Most patients receive fresh inventory monthly, which eliminates this concern when you follow the prescribed injection schedule
Until now, patients with cirrhosis caused by MASH have often been excluded from clinical trials and have had limited treatment options, making the findings particularly noteworthy
Discontinuation rates: Despite higher absolute side effect rates, discontinuation due to adverse events is similar between medications (approximately 5-7% in trials)
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