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[1] Because intrinsic-factor-dependent uptake in the distal ileum can be absent in conditions such as autoimmune gastritis, pancreatic insufficiency, or bariatric surgery, the intramuscular or subcutaneous route bypasses gastrointestinal barriers and reliably restores serum concentrations
Individuals With a History of Gastric or Bariatric Surgery Surgical procedures that alter the stomach or small intestine can significantly impair absorption of B12, folate, and other B vitamins
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Shortened telomeres are a marker of older age
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