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Oxidative stress-induced formation of methionine sulfoxide can spontaneously react with hydroxyl radical and generates methyl radical that non-specifically and non-enzymatically methylate DNA cytosine and may affect the epigenome 38
In summary, although the application of GLP-1RA in treating tumors is still in the exploratory stage, it has shown significant effects and certain additional health benefits in the treatment of diabetes
Gven, A., Gven, A., & Glmez, M
However, the precise contribution of each receptor system to overall efficacy and the potential for receptor-specific side effects remain active areas of investigation in ongoing clinical trials
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