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Symptoms of B12 deficiency include: Low energy and fatigue Digestive problems Depression and moodiness Insomnia Brain fog and memory loss Anemia Reduced immune system function Tingling or numbness in the extremities Swollen tongue Loss of vision or hearing Jaundice Kidney disease Pale skin Poor circulation in the extremities If you are over age 50 and are experiencing one or more of the above symptoms, boosting your intake of B12 cannot hurt, and it may provide a safe and inexpensive solution while preventing a wrong diagnosis

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The NAD+ salvage pathway, catalyzed by NAMPT (nicotinamide phosphoribosyltransferase), converts nicotinamide to NMN and then to NAD+

Whichever you decide on, the idea is to place the correct amount under your tongue and let it dissolve completelywithout swallowing (UMichigan Health Library, 2018)