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The FDA classified BPC-157 as a Category 2 bulk drug substance in 2023, meaning it cannot be compounded by commercial pharmaceutical companies and there is insufficient evidence regarding potential human harm

Its most distinctive physicochemical property is hydrolytic stability at low pH, unlike almost every peptide of comparable length, BPC-157 resists degradation in human gastric juice, a characteristic emphasised throughout the published work of Sikiric and colleagues (Curr Med Chem, 2012)