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According to the 2025 meta-analysis by Alfalasi and colleagues, sublingual B12 showed an approximate 199% mean increase in serum B12 compared to approximately 307% for intramuscular injections
Retrieved March 21, 2020
PMID: 41490200 Mayfield CK et al
however, this is FDA staff's proposed position going into the meeting, not a final action, and the committee's discussion, any vote, and FDA's ultimate decision are still pending, so the outcome of the review is not yet known
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