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Tumor Biol 2013;34(5):2539-2544

This is supported by recent findings that G.HCl prevented the induction of PGE 2 production by IL-1, tumor necrosis factor-, or phorbol 12-myristate 13-acetate through inhibition of COX-2 glycosylation in human skin fibroblasts 35 , and in the A549 human lung epithelial cells 28

BSO is an inhibitor of GSH synthase that has been used to deplete GSH in vitro , including in macrophages ( We analyzed the gene expression profile and identified patterns of LPS-induced genes that were inhibited by endogenous GSH or that, on the contrary, required GSH for their induction

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