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Virus protein ligands, like trimeric spike glycoprotein interact with cellular receptors, such as ACE2, and host proteases, like transmembrane protease serine 2 (TMPRSS2), participate in virus entry by proteolytically activating virus ligands (Sallenave and Guillot, 2020
Carnesecchi J, Malbouyres M, de Mets R, et al
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Exp Mol Med 52:423437
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