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Interestingly, the researchers found that lymphocytes in these patients had elevated levels of glutathione, which they hypothesize is a desperate, inadequate compensatory response by the cells trying to survive the relentless oxidative avalanche
This stimulation in the respective genes expression is possibly a part of the same mechanism to provide appropriate antioxidant defense by ensuring relevant GSH levels under conditions of oxidative stimulation by UA
Glutathione (GSH) mops up reactive oxygen species (free radicals, lipid peroxides, and heavy metals) that can cause cellular damage
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