Addressing obesity, a known risk factor and disease modifier in HS, may lead to better disease control
Samples were processed for protein isolation using RIPA buffer (Boston Bio-product, Ashland, MA) with protease inhibitors cocktail (Cell signaling technology, Danvers, MA), quantified by Pierce BCA Protein Assay Kit (Thermo Fisher Scientific, Waltham, MA) and 40 g of proteins were boiled with 4 denaturing Laemmli Sample Buffer (Bio-Rad Laboratories, Hercules, CA) and loaded on 7.5% SDS-PAGE gel
The widely used antischistosomal drug praziquantel displayed no inhibitory activity against TGR
There is no behavior or fitness coaching, and the patient community referenced is the public Reddit subreddit, not a clinic-run program