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While it is conceivable that the forces generated by Glu-induced LBD closures drive 100 rotations of subunits B and D LBDs to enter the deep desensitized state, forces that push them to rotate back upon Glu dissociation, aside from diffusion, remain unclear
Cell 130 , 10951107 (2007)
Injected peptides generally stay active longer than orally or intranasally administered ones due to better absorption and bioavailability
These signals suggest your gut has not yet adapted to the current dose level, and adding more stimulation will only make things worse
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