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GLP-1s work best in conjunction with holistic behavioral change programs: Supplementing GLP-1 use with holistic lifestyle and nutrition behavioral change management programs likely achieves the largest and most sustainable clinical benefit and cost savings, and helps overcome adherence challenges
About the prescription of exenatide and liraglutide, both compounds are contraindicated in MTC patients or multiple endocrine neoplasia syndrome 2 (MEN 2) patients due to the increased incidence of C-cell hyperplasia and tumors combined with elevated calcitonin levels in preclinical studies in rodents
Dierickx PJ et al
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