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According to the company and consistent with published pre-clinical literature, it has been studied in animal models for pre-clinical signals related to the gastrointestinal environment, inflammatory responses in the GI tract, and tissue-related processes in tendon and joint contexts - all per pre-clinical animal data, not established human clinical outcomes

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Diminished gastric function in individuals with atrophic gastritis can result in bacterial overgrowth in the small intestine and cause food-bound vitamin B 12 malabsorption