Endothelial injury generated directly by intracellular viral replication and by ACE2 downregulation, exposing cells to angiotensin II in the absence of the modulator effects of angiotensin 17 (270, 271), and vascular chronic inflammation promoting the development of tissue macrophages overloaded by cholesterol (foam cells), both increase the possibility of acquiring a severe COVID-19 infection (170, 209, 258, 259, 272, 273)
This procedure thoroughly cleans the analyzer's internal circuit, the bacteria capturing filter, and the measuring chamber
Reconstitute it immediately with bacteriostatic water and refrigerate
Individuals with known B12 deficiencies, or those prone to a potential deficiency due to their lifestyle, must supplement vitamin B12