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Adipocytes and bone marrow stromal cells in the TME can promote the resistance of tumor cells to ASNase treatment by supplying Gln and cysteine to leukemia cells, 348,349 and cancer-associated fibroblasts can secrete Asp to promote solid tumor growth
Additionally, the biological differences in genetic background and hair follicle development between mice and humans may limit the translational relevance of anwuligan for treating hair loss
Understanding the difference between lyophilized and liquid peptides is also essential for ensuring product quality
10.1126/scitranslmed.adn3079 63 KopanR.IlaganM
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