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In the autosomal recessive PD-causing genes ( PRKN , PARK7 , PINK1 , and ATP13A2 ), we identified 28 heterozygous rare variant carriers and only one homozygous rare variant carrier ( PINK1 p.L369P, Table 2)
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For downstream processing, Z-scores of proteins that had no missing values were calculated and depicted in hierarchically clustered heatmaps with the package pheatmap
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