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Unlike other nutrients, B12 requires the presence of a protein called intrinsic factor (IF) to be absorbed

Injections offer nearly 100% bioavailability, sending the vitamins directly where they are needed

For Hashimoto's patients, this discontinuation requires careful planning because: Thyroid hormone requirements increase significantly during pregnancy (typically 25-50% higher) Weight regain after GLP-1 discontinuation will change levothyroxine requirements again Optimal thyroid function before conception is critical for fetal brain development If you discover you are pregnant while on a GLP-1 medication , stop the medication immediately and contact your healthcare provider for urgent thyroid function testing and levothyroxine dose adjustment

PubMed laboratory research record [PMID: 11972973] PubMed record related to this compound for laboratory literature review