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Novo Nordisk filed an NDA for the CagriSema combination in December 2025, with an FDA decision anticipated in late 2026

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Unlike apoptosis, which involves caspase activation and nuclear fragmentation, ferroptosis is initiated by iron accumulation and lipid peroxidation, resulting in membrane rupture without caspase involvement (13)

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Target: Others

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Because growth hormone and IGF-1 support cell growth, there is a theoretical risk for individuals with active or past cancer

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