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With tirzepatide , common side effects include: Nausea Diarrhea Constipation Vomiting Stomach discomfort With retatrutide , early clinical trials show a very similar pattern so far, including: Nausea (often the most reported) Diarrhea Constipation Vomiting Dysesthesia (an abnormal skin sensation, like tingling or numbnessnot seen with tirzepatide) Lets take a look at how some of those most common side effects compare between tirzepatide and retatrutide

Lesions may also develop on the gingiva, palate, and tongue

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