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The guidelines highlight key research recommendations aligning with the recent James Lind Alliance priority-setting partnership priorities [25]
Uses Treats Vitamin B12 deficiency and pernicious anemia Supports nerve function and helps manage neuropathy Aids in red blood cell production and prevents anemia Used in the treatment of certain neurological disorders May be used as an antidote for cyanide poisoning (as prescribed by a doctor) How to Use Administered intramuscularly (IM) or intravenously (IV) by a healthcare professional
GDF15 regulates the metabolic pathways of macrophages, acquiring an anti-inflammatory function dependent on oxidative phosphorylation, reducing the expression of pro-inflammatory factors, and decreasing the infiltration of monocytes and neutrophils into the liver, thereby alleviating liver inflammation [174, 175]
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