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Glutathione neutralizes free radicals, protecting skin cells from oxidative stress that accelerates aging and deepens pigmentation and shadows

Our recent study in C57/BL6 mice exposed to CS for 1 month revealed significant downregulation in Nrf2 and its downstream protein NQO-1 levels in total brain homogenates [36], indicating a similarity in Nrf2 deficiency observed in lungs upon chronic CS exposure

It has been shown that vitamin D3 administration suppresses microglial activation in a lipopolysaccharide-activation model (62)