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T cell-derived ACh potentiates endothelial nitric oxide synthase (eNOS) activity, facilitating vasorelaxation, improving endothelial barrier integrity, and reducing inflammation-associated endothelial activation (124)

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Clinical trials demonstrate that tirzepatide produces greater average weight loss compared to semaglutide across most dosing levels

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Kivimki M, Hamer M, Batty GD, Geddes JR, Tabak AG, Pentti J, et al

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