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The downside of dulaglutide includes potential side effects such as nausea, vomiting, diarrhoea, and fatigue, particularly during early treatment

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Liraglutide administration weakened depressive- and anxiety-like behaviors in a depression mouse model of chronic administration of corticosterone and attenuated hyperactivity induced by this steroid

Furthermore, in some tumours, the need for methyl groups for epigenetic regulation prevents activation of the trans-sulphuration pathway for cysteine synthesis, instead prioritising one-carbon metabolism