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It plays a central role in oxidative-stress defense, phase II detoxification, and redox homeostasis
2f and Supplementary Data 2)
The positive effects of IGF-1 on the rats continued for months after the rats stopped getting the supplemental hormone, whereas the exercising rats immediately lost size and strength as soon as they stopped exercising. In another study the muscle fibers of 27-month old rats old age for rats that were given IGF-1 during middle age, exhibited no deterioration of muscle fibers that indicate the classic and inevitable signs of aging
Accessed August 20, 2012a
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