Mitochondrial dysfunction, a key feature of AD, further exacerbates ROS production, impairs ATP generation, disrupts calcium homeostasis, and ultimately induces neuronal apoptosis (Zhang et al., 2024)
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doi:10.1530/ec-19-0557 Cazzola M, Rogliani P, Calzetta L, Matera MG
It also reduced inflammation, lowering TLR4/NFB, TNF, and MCP1 levels, providing better protection than either agent alone (Dagar et al