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Semaglutide Side Effects (Well-Established) Common (from STEP trial data): Nausea (44%) Diarrhea (30%) Vomiting (24%) Constipation (24%) Abdominal pain (20%) Headache (14%) Serious but rare: Pancreatitis Gallbladder events (increased with rapid weight loss) Thyroid C-cell tumors (boxed warning based on animal studies) Most GI side effects are dose-dependent and improve with continued use
The best plan is personalised, sustainable, and guided by good medical advice
Differential regional effects of octreotide on human gastrointestinal motor function
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