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Based on a previous work, 30 mg/kg was considered the dose sufficient to achieve a C max comparable to the L-carnitine concentration used in vitro (1 mM) 41
Higher glucagon receptor occupancy creates greater sustained metabolic demand
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Emerging preclinical research suggests that GLP-1 receptor agonists may directly inhibit the proliferation of neoplastic cells, promote programmed cell death (apoptosis), and reduce metastatic potential through the regulation of matrix metalloproteinases and their inhibitors
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