ozempic or retatrutide Weight Loss Rival: May Work Better Retatrutide vs Ozempic: Clinical Trial

Ligand specificity GLP-2 and GLP-1 share high sequence similarity (69.7%) and have almost identical residues in two regions: the N-terminus (first six residues in GLP-2) that penetrates into the TMD core, and the C-terminus (residues 1833) that is recognized by the ECD and ECL1 of the receptor

This creates a devastating twofold crisis for the patient: their mast cells are releasing excessive amounts of endogenous histamine due to mycotoxin triggers, while their body simultaneously loses the enzymatic ability to clear that histamine

Heres why muscle loss due to GLP-1 use should raise red flags: 1

Glucagon-like peptide 2: a new treatment for chemotherapy-induced enteritis