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What the Clinical Trial Data Shows for Retatrutide Phase 2 clinical trial results, published in the New England Journal of Medicine, demonstrated that retatrutide produced mean body weight reductions of 17.5% at the 4mg dose and 24.2% at the 12mg dose over 48 weeks in adults with obesity [8]

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These beneficial effects include the counteractions of traumatic brain injury and severe encephalopathies after NSAID overdose, insulin overdose, magnesium overdose, and exposure to the neurotoxin cuprizone in a rat model of multiple sclerosis [33,34,35,36,37,38,39,40,41]

It has also been investigated for its effects on pathways related to muscle development and physical performance