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The N-terminus of GLP-2, His 1P (P indicates that the residue belongs to GLP-2), which is located above the conserved central polar network of class B GPCRs, is oriented toward TM3 and forms a hydrogen bond with H268 3.37b (Wootten numbering in superscript 27 ) and hydrophobic contacts with V271 3.40b , W340 5.36b and R344 5.40b (Fig

In this study we selected a low dose of GE2, based on prior research in rats (60) and the original study using this conjugate (59), after guidance from the Novo Nordisk team (BF, JD, BY)

(PubMed) Kwok T, Wu Y, Lee J, et al