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Animal data on LR3 infusion in pigs showed continued suppression of plasma growth hormone (~23% decrease) and IGFBP-3 across the 4-day infusion window (Tomas et al., 1997) by days 8-10 of a 10-day human community protocol, this kind of HPG-axis suppression would be expected to be active

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Research Methodology Primary Research: Interviews were conducted with endocrinologists, cardiologists, obesity medicine specialists, hospital pharmacy directors, managed care organization formulary managers, and regulatory affairs consultants