Progressive Retinaatrophie B Typ 1 (PRA-B1) Labrador Retriever mittleres Risiko

mittleres Risiko

The dog carries two copies of the dominant Ay allele for fawn/sable

The affected dogs usually have to be euthanised due to progression of the disease

that causes a symmetric bilateral necrotising myelopathy with tissue softening in the ventral and dorsal white matter

Progressive Retinaatrophie B Typ 1 (PRA-B1) Labrador Retriever mittleres RisikoProgressive retinal atrophy (PRA) in dogs is a group of genetically heterogeneous inherited retinal disorders characterized by progressive retinal degeneration and photoreceptor cell death. PRA affects over hundred dog breeds. Currently more than twenty variants in nineteen genes were associated with the disease. Clinical findings in PRA include gradual loss of vision, and attenuation of the retinal blood vessels, which result from the degeneration of