POMC - Fettleibigkeit (Labrador Retriever) Searchterm and chronic diarrhea

and chronic diarrhea

Episodes are characterized by progressive hypertonicity throughout the thoracic and pelvic limbs

The disease has a characteristic clinical phenotype

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POMC - Fettleibigkeit (Labrador Retriever) Searchterm and chronic diarrheaPOMC (proopiomelanocortin) is a gene that codes for a precursor protein that has different functions in different parts of the body, including the brain, where it is involved in regulating appetite and satiety. Mutations in this gene can lead to impaired hunger regulation and obesity. In Labrador Retrievers, a specific mutation in the POMC gene has been discovered that is associated with obesity and increased appetite. Dogs with this mutation tend to