Ehlers-Danlos Syndrom (EDS) - Dobermann Hunde DCM3 und DCM4

DCM3 und DCM4

und inspiratorische Dyspnoe

Necropsy results indicate both acute and chronic forms of disease

Mutation: ABCB4 gene

Ehlers-Danlos Syndrom (EDS) - Dobermann Hunde DCM3 und DCM4Ehlers Danlos syndrome is an autosomal recessive disorder of connective tissue that feature painful tissue fragility, skin hyper extensibility and articular hyper mobility. The clinical signs include the dogs hyper mobile carpal, tarsal and stifle joints and abnormal skin (loose and hyper elastic with several wounds and large atrophic scars). The affected dogs usually have to be euthanised due to severe injury that can result even from minimal trauma.