Protein Losing Nephropathy (PLN) Hundebesitzer-Featured paresis in the hindlimbs and

paresis in the hindlimbs and tetraparesis

lameness and dyspnea

kann aber auch bei Mischlingshunden mit Rottweiler-Abstammung gefunden werden

Die Krankheit wird als X-chromosomal vererbtes Merkmal weitergegeben

Protein Losing Nephropathy (PLN) Hundebesitzer-Featured paresis in the hindlimbs andProtein Losing Nephropathy (PLN) is a hereditary kidney disorder that causes protein leakage into urine. PLN is a late onset disease with mean age = 6. 3 2. 0 years. Because of the late onset of the disease, dogs are usually bred before diagnosis, and therefore they transmit mutated gene to their offspring. PLN is genetically complex disease and several different genes and environmental factors can contribute to the onset of symptoms. Clinical signs