Neuronale Zeroidlipofuszinose 8 (NCL-8) - Saluki ISAG Das Gehirn zeigt eine schwere

Das Gehirn zeigt eine schwere Degeneration und Nekrose von Neuronen

The dog carries two copies of the dominant D allele and expresses normal undiluted coat colour

which is an important layer of the eye under the retina

PRA has been identified in a variety of dog breeds with different inheritance patterns

Neuronale Zeroidlipofuszinose 8 (NCL-8) - Saluki ISAG Das Gehirn zeigt eine schwereNeuronal ceroid lipofuscinosis (NCLs) are a group of hereditary diseases, characterized by progressive neuronal degeneration and the accumulation of autofluorescent cytoplasmic inclusions in the brain, retina, and other tissues. Clinical symptoms and progress of the disease include increased rates of irritability, with the possibility of outbursts of aggression, hallucinations, hyperactivity and seizures. Most animals lose their ability to coordinate