Pyruvatkinasedefizienz (PK) - West Highland White Terrier Diversität because of degeneration of photoreceptor

because of degeneration of photoreceptor cells in the retina

which can damage the optic nerve and cause vision loss

Fellfarbverdünnung und neurologische Defekte (CDN) sind eine Gruppe seltener genetischer Erkrankungen

Allerdings werden nicht alle Hunde mit den Varianten DCM entwickeln

Pyruvatkinasedefizienz (PK) - West Highland White Terrier Diversität because of degeneration of photoreceptorCanine pyruvate kinase deficiency (PK deficiency) is an autosomal recessive disorder of cardiovascular system. Pyruvate kinase (PK) is essential for glycolysis in erythrocytes, which deliver oxygen to tissues. PK deficiency results in erythrocytes with decreased energy, in such ATP needed for energy cannot be synthesized, and cellular death occurs. The symptoms occur between 4 months and 1 year of age and include severe haemolytic anaemia,