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Faktor VII Defizienz (FVII) Mischling Hereditary necrotising myelopathy (HNM) is

SKU: 42500165835
4.2

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Description

Hereditary necrotising myelopathy (HNM) is an autosomal recessive inherited neurological disease in dogs

Genetic defect impairs protein physiological function in the eye

the disease develops before 4 months of age and might progress slowly

A mutation in the gene causes the improper distribution of melanosomes and coat colour dilution

Faktor VII Defizienz (FVII) Mischling Hereditary necrotising myelopathy (HNM) isFactor VII (FVII) is a vitamin K dependent coagulation factor. It is synthesized in the liver and secreted into the circulation. It plays a major role in initiation of blood coagulation. Factor VII deficiency is associated with a bleeding tendency. Clinical signs in affected dogs include mild to severe bleeding after trauma or surgery. Inheritance: autosomal recessive Mutation: Coagulation factor VII gene Genetic test: The method used for testing is

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