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Affected dogs experience unpredictable seizures with increased aggression
healthy life for your dog with additional tests
It is characterised by abnormal growth
You need a DNA profile according to ISAG 2006 for each parent (if not already available) or for each puppy or a DNA profile according to ISAG 2020
Osteogenesis Imperfecta (OI) - Beagle Startseite Affected dogs experience unpredictable seizuresOsteogenesis imperfecta is an autosomal dominant disease caused by a mutation in the COLA2 gene, which encodes collagen. Mutations altering the sequence can lead to disruptions of the collagen structure, which can lead to abnormally brittle bones that fracture very easily. The disease can be found in several dog breeds. The affected newborn puppies are exposed to fractures affecting almost every long bone right after birth and often have to be
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