Lethale Lungenerkrankung (LAMP3) Einzelanalyse Klinische Symptome bei betroffenen Welpen

Klinische Symptome bei betroffenen Welpen treten typischerweise im Alter von 6 bis 12 Wochen auf und schreiten rasch zu Status epilepticus und Tod oder Euthanasie fort

and coat colors

and petechiation

autosomal recessive - Boston Terrier

Lethale Lungenerkrankung (LAMP3) Einzelanalyse Klinische Symptome bei betroffenen WelpenLethal lung disease is a neonatal genetic disease in Airedale Terrier associated with a mutation in LEMP3 gene. Affected puppies show interstitial lung disease due to abnormal surfactant biogenesis leading to lethal hypoxic respiratory distress and failure. The clinical symptoms appear early in life, usually within the first few weeks of a puppy's life. Affected puppies show signs of rapid or shallow breathing, lethargy, pneumonia as well as other