Shedding, Haaren Für Tierbesitzer All affected dogs will develop

All affected dogs will develop POAG or PLL or both of them

muscle atrophy secondary to denervation and abnormal motor signs

notably in the respiratory tract due to impaired clearance of mucus

ISAG 2020 DNA Profile: Internationally recognized standard for identity and parentage verification

Shedding, Haaren Für Tierbesitzer All affected dogs will developReduced hair shedding (MC5R) is a complex genetic trait that can affect all breeds and has epistatic interactions with FGF5 (coat length) and RSPO2 (furnishing), which also affect hair morphology in dogs. These loci have undergone selective sweeps due to a strong artificial selection for fur phenotype. The MC5R protein sequence is evolutionarily conserved across mammals, and a certain mutation causes a conformational change in the tertiary structure